Whole-exome sequencing identifies variants in invasive pituitary adenomas

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Whole-exome sequencing identifies variants in invasive pituitary adenomas

Pituitary adenomas exhibit a wide range of behaviors. The prediction of invasion or malignant behavior in pituitary adenomas remains challenging. The objective of the present study was to identify the genetic abnormalities associated with invasion in sporadic pituitary adenomas. In the present study, the exomes of six invasive pituitary adenomas (IPA) and six non-invasive pituitary adenomas (nI...

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Whole-genome sequencing is more powerful than whole-exome sequencing for detecting exome variants.

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ژورنال

عنوان ژورنال: Oncology Letters

سال: 2016

ISSN: 1792-1074,1792-1082

DOI: 10.3892/ol.2016.5029